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| Our research is aimed at phenomena that occur at the material-tissue interface and how those interactions influence the success of implant devices. Research efforts are focused on three specific areas: 1) Surface characterization, corrosion and cytotoxicity, 2) Surface modifications, and 3) implant mechanical effects on cell development. We employ Auger Electron Spectroscopy and X-ray photoelectron spectroscopy to characterize surfaces and evaluate dental and implant alloys. Information has been correlated to corrosion and degradation processes and the effects of released corrosion products on cell viability and functions. Research has lead to the development of a novel cell culture-corrosion system, which allows for the simultaneous measurement of corrosion rates with cellular responses. Our goal is to provide data on the health benefit-risks of using implant alloy devices and on improving our understanding of how these devices perform clinically. We also investigate surface modifications using Ca-P and chitosan (a biobased polymer) coatings to promote bonding between implants and adjacent bony tissues in an effort to determine optimal coating characteristics and promote long term bonding/integration of devices into bony tissues. We investigate how mechanical forces around an implant affect development and maintenance of local bone tissues and matrix. |
